/* Local fonts and shared visual tokens */
@font-face {
  font-family:Inter;
  src:url('assets/fonts/inter-regular.woff2') format('woff2');
  font-weight:400;
  font-display:swap;
}

@font-face {
  font-family:Inter;
  src:url('assets/fonts/inter-medium.woff2') format('woff2');
  font-weight:500;
  font-display:swap;
}

@font-face {
  font-family:Inter;
  src:url('assets/fonts/inter-semibold.woff2') format('woff2');
  font-weight:600 900;
  font-display:swap;
}

/* Palette derived from the HISENSE wordmark (#62003e). No gold or navy. */
:root {
  --ink:#2b2027;
  --muted:#6d5f68;
  --accent:#62003e;
  --accent-strong:#4a002e;
  --accent-2:#8a2462;
  --accent-soft:#f7eef4;
  --surface:#faf6f9;
  --line:#eae1e6;
  --header-height:76px;
}

* {
  box-sizing:border-box;
}

html {
  scroll-behavior:smooth;
  scroll-padding-top:calc(var(--header-height) + 26px);
}

body {
  margin:0;
  color:var(--ink);
  background:#fff;
  font-family:Inter,Arial,sans-serif;
  font-size:17px;
  line-height:1.75;
  -webkit-font-smoothing:antialiased;
}

::selection {
  background:#f3dfec;
  color:var(--accent);
}

a {
  color:inherit;
  text-decoration:none;
  text-underline-offset:4px;
}

button {
  font:inherit;
}

a,button {
  -webkit-tap-highlight-color:transparent;
}

a:focus-visible,button:focus-visible {
  outline:3px solid var(--accent);
  outline-offset:5px;
  border-radius:4px;
}

main:focus,section:focus {
  outline:none;
}

img {
  display:block;
  max-width:100%;
  height:auto;
}

h1,h2,h3,h4,p {
  margin:0;
}

h1,h2,h3,h4 {
  font-weight:600;
  line-height:1.16;
  letter-spacing:-.03em;
}

.container {
  width:min(1200px,calc(100% - 104px));
  margin-inline:auto;
}

.skip-link {
  position:fixed;
  left:20px;
  top:-100px;
  padding:12px 22px;
  background:var(--ink);
  color:#fff;
  z-index:100;
}

.skip-link:focus {
  top:12px;
}

.eyebrow {
  display:flex;
  align-items:center;
  gap:11px;
  margin-bottom:22px;
  font-size:12px;
  font-weight:600;
  letter-spacing:.16em;
  text-transform:uppercase;
  color:var(--muted);
}

.small-label,.footer-label {
  font-size:11px;
  letter-spacing:.13em;
  text-transform:uppercase;
  font-weight:600;
}

.accent-line {
  width:24px;
  height:2px;
  background:var(--accent);
  flex-shrink:0;
}

.accent-text {
  color:var(--accent);
}

.section {
  padding-block:100px;
}

.section-head {
  margin-bottom:46px;
}

.head-row {
  display:grid;
  grid-template-columns:1.12fr .88fr;
  gap:72px;
  align-items:end;
}

h2 {
  font-size:clamp(38px,3.4vw,54px);
  line-height:1.12;
  letter-spacing:-.02em;
  text-wrap:balance;
}

.intro-copy {
  color:var(--muted);
  font-size:17px;
  line-height:1.85;
}

.intro-copy p+p {
  margin-top:15px;
}

/* Body text: justified across the page (labels, eyebrows and captions excluded) */
.hero-name,
.hero-lead,
.intro-copy,
.pillar p,
.disease-card p,
.impact-card p,
.publication .publication-summary,
.preliminary p:not(.small-label):not(.eyebrow),
.challenge-box p:not(.small-label):not(.eyebrow),
.team-growth p,
.person p,
.pi-description,
.news-layout p:not(.eyebrow),
.news-empty p,
.footer-funding p,
.funding p,
.research-steps li p,
.steps-note p {
  text-align:justify;
  text-justify:inter-word;
}

/* Persistent navigation; breakpoint shared with script.js. */
.site-header {
  position:sticky;
  top:0;
  background:rgba(255,255,255,.96);
  backdrop-filter:blur(8px);
  border-bottom:1px solid var(--line);
  z-index:20;
}

.header-inner {
  min-height:var(--header-height);
  display:flex;
  align-items:center;
  justify-content:space-between;
  gap:28px;
}

.brand {
  display:block;
  width:150px;
  flex-shrink:0;
  padding:9px 0;
}

.brand-img {
  width:100%;
  height:auto;
}

nav {
  display:flex;
  align-items:center;
  gap:32px;
}

nav a {
  position:relative;
  font-size:15px;
  font-weight:500;
  padding:14px 0;
  white-space:nowrap;
  color:var(--muted);
}

nav a::after {
  content:'';
  position:absolute;
  bottom:6px;
  left:0;
  right:0;
  height:2px;
  background:var(--accent);
  transform:scaleX(0);
  transform-origin:left;
  transition:transform .2s;
}

nav a:hover,nav a[aria-current] {
  color:var(--accent);
}

nav a:hover::after,nav a[aria-current]::after {
  transform:scaleX(1);
}

nav a.nav-cta {
  min-height:42px;
  padding:10px 22px;
  border-radius:999px;
  background:var(--accent);
  border:1px solid var(--accent);
  color:#fff;
  font-size:14px;
  font-weight:600;
  box-shadow:0 4px 14px #62003e1f;
  transition:background .2s,transform .2s,border-color .2s,color .2s;
}

nav a.nav-cta::after {
  display:none;
}

nav a.nav-cta:hover {
  background:var(--accent-strong);
  border-color:var(--accent-strong);
  color:#fff;
  transform:translateY(-1px);
}

nav a.nav-cta[aria-current] {
  color:#fff;
  background:var(--accent-strong);
  border-color:var(--accent-strong);
}

.menu-toggle {
  display:none;
}

/* Hero */
.hero {
  padding-block:44px 0;
  background:linear-gradient(180deg,#fff 0%,#fffdfe 100%);
}

.hero-grid {
  display:grid;
  grid-template-columns:1.08fr .92fr;
  gap:64px;
  align-items:center;
}

.hero-copy {
  padding-block:14px 30px;
}

h1 {
  font-size:clamp(38px,3.8vw,58px);
  letter-spacing:-.04em;
  line-height:1.08;
  text-wrap:balance;
}

.hero-name {
  font-size:17px;
  line-height:1.65;
  color:var(--muted);
  max-width:610px;
  margin-top:24px;
}

.hero-name strong {
  color:var(--ink);
  font-weight:600;
}

.hero-lead {
  font-size:18px;
  line-height:1.8;
  color:var(--muted);
  max-width:560px;
  margin-top:20px;
}

.hero-actions {
  display:flex;
  flex-wrap:wrap;
  gap:14px;
  margin-top:32px;
}

.hero-meta {
  display:flex;
  flex-wrap:wrap;
  gap:0;
  margin:34px 0 0;
  padding:22px 0 0;
  border-top:1px solid var(--line);
}

.hero-meta-item {
  flex:1 1 0;
  min-width:0;
  padding:0 26px;
}

.hero-meta-item:first-child {
  padding-left:0;
}

.hero-meta-item+.hero-meta-item {
  border-left:1px solid var(--line);
}

.hero-meta dt {
  font-size:11px;
  letter-spacing:.13em;
  text-transform:uppercase;
  font-weight:600;
  color:var(--muted);
  margin-bottom:7px;
}

.hero-meta dd {
  margin:0;
  font-size:16px;
  font-weight:500;
  letter-spacing:-.01em;
  color:var(--accent);
}

.button {
  display:inline-flex;
  align-items:center;
  justify-content:center;
  min-height:50px;
  padding:13px 27px;
  background:var(--accent);
  color:#fff;
  border:1px solid var(--accent);
  border-radius:999px;
  font-size:16px;
  font-weight:500;
  box-shadow:0 6px 18px #62003e1f;
  transition:background .2s,transform .2s,border-color .2s,color .2s;
}

.button:hover {
  background:var(--accent-strong);
  border-color:var(--accent-strong);
  transform:translateY(-2px);
}

.button-ghost {
  background:#fff;
  color:var(--ink);
  border-color:#d9c6d2;
  box-shadow:none;
}

.button-ghost:hover {
  background:var(--accent-soft);
  border-color:var(--accent);
  color:var(--accent);
}

.hero-visual {
  display:flex;
  align-items:center;
  justify-content:center;
  border-radius:20px;
  background:linear-gradient(150deg,#fbf4fa,#f2e6f0);
  border:1px solid #f0e2ec;
  padding:34px 26px;
}

.hero-visual img {
  width:100%;
  max-width:520px;
}

.funding {
  display:flex;
  align-items:center;
  justify-content:space-between;
  gap:36px;
  margin-top:40px;
  padding:26px 0 30px;
  border-top:1px solid var(--line);
}

.funding p {
  font-size:14px;
  color:var(--muted);
  line-height:1.9;
}

.funding-label {
  display:block;
  font-size:11px;
  font-weight:600;
  letter-spacing:.13em;
  text-transform:uppercase;
  color:var(--ink);
  margin-bottom:8px;
}

.funding a,.footer-funding a {
  text-decoration:underline;
  text-decoration-color:#c3aebc;
}

.funding a:hover,.footer-funding a:hover {
  text-decoration-color:var(--accent);
  color:var(--accent);
}

.institutional-logos {
  width:320px;
  padding:45px;
  flex-shrink:0;
  box-sizing:content-box;
}

.institutional-logos img {
  width:100%;
}

/* About: paragraphs sit directly under the title */
.about .head-row {
  grid-template-columns:1fr;
  gap:26px;
}

/* About: purpose, facts and the research journey */
.project-facts {
  display:grid;
  grid-template-columns:.62fr 1.25fr 1fr;
  align-items:center;
  gap:30px;
  margin:34px 0 46px;
  padding:26px 0;
  border-block:1px solid var(--line);
}

.fact {
  display:flex;
  flex-direction:column;
  gap:4px;
}

.fact+.fact {
  border-left:1px solid var(--line);
  padding-left:34px;
}

.fact-number {
  font-size:62px;
  font-weight:500;
  line-height:1;
  letter-spacing:-.06em;
  color:var(--accent);
}

.fact-label {
  font-size:11px;
  letter-spacing:.12em;
  text-transform:uppercase;
  font-weight:600;
  color:var(--muted);
}

.fact p {
  font-size:16px;
  line-height:1.7;
  margin-top:8px;
}

.fact-accent {
  color:var(--accent);
}

.challenge-box {
  display:flex;
  align-items:center;
  gap:26px;
  margin:0 0 46px;
  padding:30px 34px;
  background:var(--accent-soft);
  border:1px solid #e8cfe0;
  border-radius:18px;
}

.challenge-marker {
  display:flex;
  align-items:center;
  justify-content:center;
  flex-shrink:0;
  width:56px;
  height:56px;
  border-radius:50%;
  background:#fff;
  color:var(--accent);
  font-size:24px;
  font-weight:700;
  border:1px solid #e8cfe0;
}

.challenge-box .small-label {
  display:block;
  color:var(--accent);
}

.challenge-box h3 {
  font-size:24px;
  letter-spacing:-.03em;
  margin-top:7px;
  margin-bottom:11px;
}

.challenge-box p {
  font-size:15px;
  line-height:1.85;
  color:var(--muted);
  max-width:62ch;
}

.challenge-box strong {
  color:var(--ink);
  font-weight:600;
}

.steps-panel {
  border-radius:18px;
  background:var(--surface);
  border:1px solid #efe3ec;
  padding:36px 34px 30px;
}

.steps-head {
  display:flex;
  align-items:end;
  justify-content:space-between;
  gap:24px;
  margin-bottom:30px;
}

.steps-head .eyebrow {
  margin-bottom:12px;
  font-size:11px;
}

.steps-head h3 {
  font-size:30px;
  letter-spacing:-.035em;
}

.steps-sub {
  color:var(--muted);
  font-size:14px;
  line-height:1.8;
  text-align:right;
}

.research-steps {
  display:grid;
  grid-template-columns:repeat(4,1fr);
  gap:18px;
  list-style:none;
  margin:0;
  padding:0;
}

.research-steps li {
  min-width:0;
  background:#fff;
  border:1px solid var(--line);
  border-radius:14px;
  padding:24px 22px;
  transition:border-color .2s;
}

.research-steps li:hover {
  border-color:#d4bfce;
}

.step-icon {
  display:flex;
  align-items:center;
  justify-content:center;
  width:52px;
  height:52px;
  border-radius:12px;
  background:var(--accent-soft);
}

.step-icon img {
  width:30px;
  height:30px;
}

.step-no {
  display:block;
  font-size:11px;
  letter-spacing:.14em;
  text-transform:uppercase;
  font-weight:600;
  color:var(--accent);
  margin-top:20px;
}

.research-steps h4 {
  font-size:20px;
  line-height:1.3;
  margin:9px 0 10px;
}

.research-steps p {
  font-size:15px;
  line-height:1.8;
  color:var(--muted);
}

.steps-note {
  display:flex;
  align-items:center;
  gap:15px;
  margin-top:20px;
  padding:18px 22px;
  background:#fff;
  border:1px solid var(--line);
  border-radius:12px;
}

.note-symbol {
  color:var(--accent);
  font-size:26px;
  line-height:1;
}

.steps-note p {
  font-size:14px;
  line-height:1.75;
  color:var(--muted);
}

.steps-note strong {
  color:var(--ink);
  font-weight:600;
}

/* Why: three transverse dimensions */
.pillars {
  display:grid;
  grid-template-columns:repeat(3,1fr);
  gap:22px;
  list-style:none;
  margin:0;
  padding:0;
}

.pillar {
  position:relative;
  padding:30px 28px 28px;
  background:#fff;
  border:1px solid var(--line);
  border-radius:16px;
  overflow:hidden;
  transition:border-color .2s,transform .2s,box-shadow .2s;
}

.pillar:hover {
  border-color:#d4bfce;
  transform:translateY(-3px);
  box-shadow:0 12px 30px #62003e12;
}

.pillar-no {
  position:absolute;
  top:22px;
  right:24px;
  font-size:15px;
  font-weight:600;
  letter-spacing:.08em;
  color:#cbb3c3;
}

.pillar-icon {
  display:flex;
  align-items:center;
  justify-content:center;
  width:54px;
  height:54px;
  border-radius:13px;
  background:var(--accent-soft);
}

.pillar-icon img {
  width:30px;
  height:30px;
}

.pillar h3 {
  font-size:23px;
  letter-spacing:-.03em;
  margin:20px 0 10px;
}

.pillar p {
  font-size:15px;
  line-height:1.8;
  color:var(--muted);
}

.pillar-practice {
  margin-top:18px;
  padding:15px 17px;
  border-left:3px solid var(--accent);
  background:var(--accent-soft);
  border-radius:0 10px 10px 0;
  font-size:14px;
  line-height:1.75;
  color:#5a4b53;
}

.pillar-practice span {
  display:block;
  font-size:11px;
  font-weight:600;
  letter-spacing:.12em;
  text-transform:uppercase;
  color:var(--accent);
  margin-bottom:5px;
}

/* Conditions studied */
.disease-grid {
  display:grid;
  grid-template-columns:repeat(3,1fr);
  gap:22px;
}

.disease-card {
  display:flex;
  flex-direction:column;
  padding:28px 27px 30px;
  border:1px solid #eae0e8;
  border-top:3px solid var(--accent-2);
  border-radius:14px;
  background:var(--surface);
  transition:border-color .2s,transform .2s,background .2s;
}

.disease-card:hover {
  border-color:#d8bcd2;
  border-top-color:var(--accent-2);
  background:#fff;
  transform:translateY(-3px);
}

.disease-top {
  display:flex;
  align-items:baseline;
  justify-content:space-between;
  gap:12px;
  margin-bottom:14px;
}

.disease-top h3 {
  font-size:24px;
  letter-spacing:-.03em;
  display:flex;
  flex-direction:column;
  gap:4px;
}

.disease-top h3 span {
  font-size:13px;
  font-weight:400;
  letter-spacing:0;
  color:var(--muted);
}

.disease-tag {
  flex-shrink:0;
  font-size:10px;
  font-weight:600;
  letter-spacing:.1em;
  text-transform:uppercase;
  color:var(--accent-2);
  background:#f4e5ee;
  border-radius:999px;
  padding:5px 10px;
}

.disease-card p {
  font-size:15px;
  line-height:1.8;
  color:var(--muted);
}

.disease-also {
  margin-top:12px;
  padding-top:14px;
  border-top:1px solid #ecd6e5;
  font-size:14px;
  line-height:1.75;
  color:#5a4b53;
}

/* Expected impact */
.impact {
  background:var(--surface);
}

.impact-grid {
  display:grid;
  grid-template-columns:repeat(3,1fr);
  gap:20px;
}

.impact-card {
  position:relative;
  padding:27px 26px 28px;
  border:1px solid #e9dfe7;
  border-radius:14px;
  background:#fff;
  transition:border-color .2s,transform .2s,box-shadow .2s;
}

.impact-card:hover {
  border-color:#cfa9c0;
  transform:translateY(-3px);
  box-shadow:0 12px 30px #62003e12;
}

.impact-no {
  font-size:13px;
  font-weight:600;
  letter-spacing:.1em;
  color:var(--accent);
}

.impact-card h3 {
  font-size:21px;
  letter-spacing:-.03em;
  margin:14px 0 10px;
}

.impact-card p {
  font-size:15px;
  line-height:1.8;
  color:var(--muted);
}

/* Reveal-on-scroll micro-interaction (progressive enhancement) */
.js .reveal {
  opacity:0;
  transform:translateY(16px);
  transition:opacity .6s ease,transform .6s ease;
}

.js .reveal.is-visible {
  opacity:1;
  transform:none;
}

/* Team */
.team {
  background:var(--surface);
}

.team-layout {
  display:grid;
  gap:28px;
}

.pi-card {
  position:relative;
  display:grid;
  grid-template-columns:130px 1fr 1.15fr;
  align-items:center;
  gap:28px;
  padding:30px 34px;
  background:#fff;
  border:1px solid #e8d9e4;
  border-left:4px solid var(--accent);
  border-radius:16px;
  transition:transform .25s ease, box-shadow .25s ease, border-color .25s ease;
}

.pi-card:hover {
  transform:translateY(-4px);
  box-shadow:0 22px 48px -20px rgba(43,32,39,.30);
}

.pi-photo {
  width:120px;
  height:120px;
  border-radius:50%;
  object-fit:cover;
  border:4px solid var(--accent-soft);
  transition:box-shadow .25s ease;
}

.pi-card:hover .pi-photo {
  box-shadow:0 0 0 4px var(--accent-soft);
}

.pi-role {
  color:var(--accent);
  font-size:12px;
  letter-spacing:.13em;
  text-transform:uppercase;
  font-weight:600;
  margin-bottom:8px;
}

.pi-card h3 {
  font-size:30px;
  letter-spacing:-.035em;
}

.pi-institution {
  font-size:16px;
  color:var(--muted);
  margin-top:9px;
}

.pi-expertise {
  padding-left:30px;
  border-left:1px solid var(--line);
}

.pi-expertise .small-label {
  color:var(--muted);
}

.pi-description {
  font-size:15px;
  line-height:1.8;
  color:var(--muted);
  margin-top:10px;
  max-width:440px;
}

.pi-footer {
  display:block;
  color:var(--accent);
  font-size:13px;
  font-weight:500;
  margin-top:16px;
}

.team-groups {
  display:grid;
  grid-template-columns:1fr 1fr;
  gap:28px;
}

.team-group {
  display:grid;
  grid-template-columns:1fr 1fr;
  gap:18px;
  align-content:start;
}

.team-group>h3 {
  grid-column:1 / -1;
  display:flex;
  flex-direction:column;
  gap:6px;
  font-size:18px;
  line-height:1.4;
  padding:0 0 14px;
  border-bottom:2px solid var(--accent);
}

.team-group>h3 span {
  font-size:13px;
  font-weight:400;
  color:var(--muted);
}

.person {
  background:#fff;
  padding:23px 21px;
  border:1px solid #eae0e8;
  border-radius:12px;
  transition:transform .25s ease, box-shadow .25s ease, border-color .25s ease;
}

.person:hover {
  transform:translateY(-5px);
  box-shadow:0 18px 40px -18px rgba(43,32,39,.28);
  border-color:#dcbdd2;
}

.person-photo {
  width:76px;
  height:76px;
  border-radius:16px;
  object-fit:cover;
  border:2px solid var(--line);
  margin-bottom:20px;
  transition:box-shadow .25s ease;
}

.person:hover .person-photo {
  box-shadow:0 0 0 4px var(--accent-soft);
}

.person h4 {
  font-size:21px;
  letter-spacing:-.035em;
  margin-bottom:9px;
}

.person .person-role {
  font-size:13px;
  font-weight:500;
  line-height:1.6;
  color:var(--accent);
  margin-bottom:12px;
}

.person p {
  font-size:15px;
  line-height:1.8;
  color:var(--muted);
}

.clinical-group>h3 {
  border-color:var(--accent-2);
}

.clinical-group .person-role {
  color:var(--accent-2);
}

.clinical-group .person-photo {
  border:2px solid #e9d3e2;
}

.clinical-group .person:hover .person-photo {
  box-shadow:0 0 0 4px #f0d9e8;
}

@media(hover:none) {
  .person:hover,
  .pi-card:hover {
    transform:none;
    box-shadow:none;
  }
}

.profile-link {
  display:inline-flex;
  align-items:center;
  gap:6px;
  margin-top:12px;
  font-size:11px;
  font-weight:600;
  letter-spacing:.13em;
  text-transform:uppercase;
  color:var(--accent);
}

.clinical-group .profile-link {
  color:var(--accent-2);
}

.profile-arrow {
  font-size:12px;
  transition:transform .2s ease;
}

.profile-link:hover .profile-arrow {
  transform:translate(2px,-2px);
}

.team-growth {
  display:flex;
  align-items:center;
  gap:16px;
  margin-top:24px;
  padding:18px 22px;
  background:#fff;
  border:1px solid #eadbe6;
  border-radius:12px;
  font-size:15px;
  color:var(--muted);
}

.team-growth strong {
  color:var(--ink);
  font-weight:600;
}

.growth-mark {
  font-size:28px;
  line-height:1;
  color:var(--accent);
}

/* Publications and outcomes */
.outcomes-status {
  display:flex;
  align-items:center;
  gap:20px;
  padding:20px 24px;
  background:var(--accent-soft);
  border-radius:12px;
  margin-bottom:44px;
}

.status-icon {
  color:var(--accent);
  font-size:30px;
  line-height:1;
}

.outcomes-status h3 {
  font-size:18px;
  margin-bottom:5px;
}

.outcomes-status p {
  font-size:15px;
  color:var(--muted);
}

.status-label {
  margin-left:auto;
  white-space:nowrap;
  font-size:12px;
  font-weight:600;
  background:#fff;
  color:var(--accent);
  border:1px solid #e6cddc;
  border-radius:999px;
  padding:6px 13px;
}

.preliminary {
  margin-bottom:44px;
  padding:34px 36px;
  background:var(--surface);
  border:1px solid #efe3ec;
  border-radius:18px;
}

.prelim-head {
  margin-bottom:24px;
}

.prelim-head .eyebrow {
  margin-bottom:12px;
}

.prelim-head p:not(.eyebrow) {
  font-size:15px;
  line-height:1.8;
  color:var(--muted);
  max-width:78ch;
}

.prelim-head strong {
  color:var(--ink);
  font-weight:600;
}

.prelim-stats {
  display:grid;
  grid-template-columns:repeat(4,1fr);
  gap:16px;
  margin-bottom:22px;
}

.prelim-stat {
  display:flex;
  flex-direction:column;
  gap:5px;
  padding:22px 22px 20px;
  background:#fff;
  border:1px solid #e9dfe7;
  border-radius:14px;
}

.prelim-stat strong {
  font-size:44px;
  font-weight:600;
  line-height:1;
  letter-spacing:-.05em;
  color:var(--accent);
}

.prelim-stat span {
  font-size:14px;
  line-height:1.6;
  color:var(--muted);
}

.prelim-copy {
  font-size:15px;
  line-height:1.85;
  color:var(--muted);
  max-width:96ch;
  margin:0;
}

.publication-heading {
  margin-bottom:22px;
}

.publication-heading h3 {
  font-size:24px;
  letter-spacing:-.025em;
  margin-bottom:7px;
}

.publication-heading p {
  font-size:15px;
  color:var(--muted);
}

.publication {
  display:grid;
  grid-template-columns:230px 1fr;
  align-items:center;
  gap:34px;
  padding-block:28px;
  border-top:1px solid var(--line);
}

.publication:last-child {
  border-bottom:1px solid var(--line);
}

.publication-visual img {
  width:100%;
  border-radius:12px;
  border:1px solid #f0e4ec;
}

.publication-content {
  min-width:0;
}

.publication-meta {
  display:flex;
  gap:12px;
  align-items:center;
  flex-wrap:wrap;
  color:var(--muted);
  font-size:13px;
  line-height:1.6;
  margin-bottom:13px;
}

.publication-type {
  color:var(--accent);
  background:var(--accent-soft);
  border-radius:999px;
  font-size:11px;
  font-weight:600;
  letter-spacing:.05em;
  padding:4px 11px;
}

.publication h4 {
  font-size:23px;
  line-height:1.4;
  letter-spacing:-.03em;
}

.publication h4 a {
  display:block;
  position:relative;
  padding-right:30px;
}

.publication h4 a:hover {
  color:var(--accent);
  text-decoration:underline;
  text-decoration-thickness:1px;
}

.publication-arrow {
  position:absolute;
  right:0;
  top:0;
  font-size:26px;
  color:var(--accent);
}

.authors {
  font-size:14px;
  color:var(--muted);
  margin-top:9px;
}

.publication-summary {
  font-size:15px;
  color:var(--muted);
  line-height:1.85;
  margin-top:11px;
  max-width:760px;
}

.text-link {
  display:inline-flex;
  align-items:center;
  gap:10px;
  color:var(--accent);
  font-size:14px;
  font-weight:600;
  margin-top:11px;
  min-height:32px;
}

.text-link:hover {
  text-decoration:underline;
}

/* News and contacts */
.news {
  background:var(--surface);
}

.news-layout {
  display:grid;
  grid-template-columns:1.05fr .95fr;
  gap:64px;
  align-items:center;
}

.news-layout h2 {
  font-size:clamp(33px,3vw,44px);
}

.news-layout>div>p:not(.eyebrow) {
  color:var(--muted);
  font-size:17px;
  line-height:1.8;
  margin-top:18px;
  max-width:430px;
}

.news-empty {
  display:flex;
  gap:22px;
  align-items:center;
  padding:30px;
  background:#fff;
  border:1px dashed #cdb6c6;
  border-radius:16px;
}

.news-illustration {
  width:125px;
  flex-shrink:0;
}

.news-empty .small-label {
  color:var(--accent);
}

.news-empty h3 {
  font-size:25px;
  letter-spacing:-.03em;
  margin-top:8px;
}

.news-empty p {
  font-size:15px;
  color:var(--muted);
  line-height:1.8;
  margin-top:9px;
}

.contacts {
  background:#fff;
}

.contact-grid {
  display:grid;
  grid-template-columns:1fr 1fr;
  gap:24px;
}

.contact-card {
  position:relative;
  padding:29px 31px;
  border:1px solid #e9dfe7;
  border-radius:14px;
  background:#fff;
  transition:border-color .2s,transform .2s,background .2s;
}

.contact-card:hover {
  border-color:#cfa9c0;
  background:#fdfafc;
  transform:translateY(-3px);
}

.contact-logo,.contact-logo-unina {
  display:block;
  width:auto;
  height:40px;
  margin-bottom:22px;
}

.contact-card>.small-label {
  color:var(--muted);
}

.contact-card h3 {
  font-size:29px;
  letter-spacing:-.035em;
  margin-top:0;
}

.contact-card h3 span {
  font-size:22px;
  color:var(--accent);
  margin-left:8px;
}

.contact-card p {
  font-size:15px;
  line-height:1.85;
  color:var(--muted);
  margin-top:13px;
  margin-bottom:24px;
}

.contact-url {
  color:var(--accent);
  font-size:15px;
  font-weight:500;
  text-decoration:underline;
  text-decoration-color:#c9adbe;
  text-underline-offset:4px;
}

.contact-card:hover .contact-url {
  text-decoration-color:var(--accent);
}

/* Footer */
.site-footer {
  background:#fff;
  border-top:1px solid var(--line);
  padding-top:44px;
}

.footer-grid {
  display:grid;
  grid-template-columns:1.25fr .8fr 1.3fr;
  gap:52px;
  padding-bottom:38px;
  border-bottom:1px solid var(--line);
}

.footer-brand {
  display:block;
  width:190px;
}

.footer-brand-col p {
  font-size:14px;
  line-height:1.8;
  color:var(--muted);
  margin-top:16px;
}

.footer-nav {
  display:flex;
  flex-direction:column;
  align-items:start;
  gap:9px;
}

.footer-nav .footer-label,.footer-funding .footer-label {
  color:var(--muted);
  margin-bottom:7px;
}

.footer-nav a {
  font-size:15px;
  color:var(--muted);
}

.footer-nav a:hover {
  color:var(--accent);
}

.footer-funding {
  display:flex;
  flex-direction:column;
  align-items:start;
}

.footer-funding p {
  font-size:13px;
  line-height:1.9;
  color:var(--muted);
  margin-bottom:20px;
}

.footer-funding .institutional-logos {
  width:270px;
  padding:38px;
}

.footer-bottom {
  display:flex;
  align-items:center;
  justify-content:space-between;
  gap:15px;
  padding-block:18px;
  color:var(--muted);
  font-size:12px;
  letter-spacing:.04em;
}

@media(max-width:1150px) {
  .container {
    width:calc(100% - 64px);
  }
  nav {
    gap:22px;
  }
  nav a {
    font-size:14px;
  }
  nav a.nav-cta {
    min-height:38px;
    padding:8px 18px;
    font-size:13px;
  }
  .brand {
    width:140px;
  }
  .hero-grid {
    gap:40px;
  }
  .hero-visual {
    padding:26px 18px;
  }
  .institutional-logos {
    width:280px;
    padding:40px;
  }
  .head-row {
    gap:48px;
  }
  .steps-panel {
    padding:30px 26px 26px;
  }
  .research-steps {
    gap:14px;
  }
  .pillars,.disease-grid,.impact-grid {
    gap:16px;
  }
  .hero-meta-item {
    padding:0 20px;
  }
  .research-steps li {
    padding:21px 18px;
  }
  .team-group {
    grid-template-columns:1fr;
  }
  .team-groups {
    gap:20px;
  }
  .pi-card {
    grid-template-columns:118px 1fr 1.1fr;
    gap:24px;
    padding:27px;
  }
  .pi-photo {
    width:110px;
    height:110px;
  }
  .pi-card h3 {
    font-size:27px;
  }
  .publication {
    grid-template-columns:200px 1fr;
    gap:28px;
  }
  .news-layout {
    gap:40px;
  }
  .footer-grid {
    gap:36px;
  }
}

/* Tablet navigation and intermediate compositions */
@media(max-width:900px) {
  :root {
    --header-height:66px;
  }
  .header-inner {
    flex-wrap:wrap;
    gap:0;
  }
  .brand {
    width:144px;
  }
  .menu-toggle:not([hidden]) {
    display:flex;
    gap:12px;
    align-items:center;
    justify-content:center;
    color:var(--ink);
    font-size:14px;
    min-height:44px;
    padding:8px 14px;
    border:1px solid var(--line);
    border-radius:999px;
    background:#fff;
  }
  .menu-icon {
    position:relative;
    width:17px;
    height:12px;
    border-block:1px solid;
  }
  .menu-icon::after {
    content:'';
    position:absolute;
    top:4.5px;
    left:0;
    right:0;
    border-top:1px solid;
  }
  .menu-toggle[aria-expanded=true] .menu-icon {
    border:0;
  }
  .menu-toggle[aria-expanded=true] .menu-icon::before,.menu-toggle[aria-expanded=true] .menu-icon::after {
    content:'';
    position:absolute;
    top:5px;
    left:0;
    right:0;
    border-top:1px solid;
    transform:rotate(45deg);
  }
  .menu-toggle[aria-expanded=true] .menu-icon::after {
    transform:rotate(-45deg);
  }
  nav {
    width:100%;
    flex-wrap:wrap;
    gap:0 22px;
    padding-bottom:14px;
  }
  nav a {
    font-size:15px;
    color:var(--ink);
  }
  nav a.nav-cta {
    color:#fff;
  }
  .js nav {
    display:none;
  }
  .js nav.is-open {
    display:flex;
    flex-direction:column;
    align-items:stretch;
    gap:0;
    padding:12px 0 22px;
  }
  .js nav a {
    padding:13px 0;
    border-bottom:1px solid var(--line);
  }
  .js nav a:last-child {
    border-bottom:0;
  }
  .js nav a::after {
    right:auto;
    width:28px;
    bottom:6px;
  }
  .js nav .nav-cta {
    margin-top:16px;
  }
  .js nav a.nav-cta {
    padding:10px 22px;
    text-align:center;
    color:#fff;
    border-bottom:0;
  }
  .js nav a.nav-cta::after {
    display:none;
  }
  .hero {
    padding-block:36px 0;
  }
  .hero-grid {
    grid-template-columns:1.1fr .9fr;
    gap:34px;
  }
  h1 {
    font-size:38px;
  }
  .hero-lead {
    font-size:17px;
  }
  .hero-visual img {
    max-width:430px;
  }
  .funding {
    gap:22px;
  }
  .funding p {
    font-size:13px;
  }
  .section {
    padding-block:80px;
  }
  .section-head {
    margin-bottom:38px;
  }
  .head-row {
    gap:36px;
  }
  h2 {
    font-size:42px;
  }
  .intro-copy {
    font-size:16px;
  }
  .project-facts {
    gap:22px;
    margin-block:30px 40px;
  }
  .fact+.fact {
    padding-left:22px;
  }
  .fact-number {
    font-size:52px;
  }
  .fact p {
    font-size:14px;
  }
  .steps-head h3 {
    font-size:27px;
  }
  .steps-sub {
    font-size:13px;
  }
  .research-steps {
    grid-template-columns:repeat(2,1fr);
  }
  .pillars,.disease-grid {
    grid-template-columns:1fr;
  }
  .impact-grid {
    grid-template-columns:1fr 1fr;
  }
  .impact-grid .impact-card:last-child {
    grid-column:1 / -1;
  }
  .hero-meta {
    padding-top:18px;
  }
  .hero-meta dd {
    font-size:15px;
  }
  .prelim-stats {
    grid-template-columns:1fr 1fr;
  }
  .prelim-stat strong {
    font-size:38px;
  }
  .challenge-box {
    gap:20px;
    padding:26px 24px;
  }
  .pi-card {
    grid-template-columns:108px 1fr 1.1fr;
    gap:20px;
    padding:26px;
  }
  .pi-photo {
    width:100px;
    height:100px;
  }
  .pi-card h3 {
    font-size:26px;
  }
  .pi-expertise {
    padding-left:22px;
  }

  .team-group {
    grid-template-columns:1fr 1fr;
  }
  .person {
    padding:24px 22px;
  }
  .person-photo {
    width:68px;
    height:68px;
    border-radius:14px;
  }
  .person h4 {
    font-size:21px;
  }
  .publication {
    grid-template-columns:180px 1fr;
    gap:26px;
  }
  .publication h4 {
    font-size:21px;
  }
  .news-layout {
    gap:34px;
  }
  .news-empty {
    padding:24px;
    gap:18px;
  }
  .news-illustration {
    width:105px;
  }
  .contact-card {
    padding:25px;
  }
  .contact-card h3 {
    font-size:26px;
  }
  .footer-grid {
    grid-template-columns:1fr 1fr;
    gap:34px;
  }
  .footer-funding {
    grid-column:1 / -1;
  }
  .footer-funding .institutional-logos {
    width:min(220px, calc(100vw - 140px));
    padding:26px;
  }
}

/* Mobile: one continuous reading path */
@media(max-width:650px) {
  .container {
    width:calc(100% - 40px);
  }
  .hero {
    padding-block:28px 0;
  }
  .hero-grid {
    grid-template-columns:1fr;
    gap:26px;
  }
  .hero-copy {
    padding-block:6px 0;
  }
  h1 {
    font-size:clamp(33px,7vw,42px);
    line-height:1.12;
  }
  .hero-name {
    font-size:16px;
    margin-top:20px;
  }
  .hero-lead {
    font-size:17px;
    margin-top:17px;
  }
  .hero-actions {
    margin-top:26px;
  }
  .button {
    flex:1 1 auto;
  }
  .hero-visual {
    padding:22px 14px;
    border-radius:16px;
  }
  .funding {
    flex-direction:column;
    align-items:start;
    gap:2px;
    margin-top:30px;
    padding:22px 0 26px;
  }
  .funding p {
    font-size:13px;
  }
  .institutional-logos {
    width:calc(100% * 7 / 9);
    max-width:290px;
    padding:calc(100% / 9);
    align-self:center;
  }
  .section {
    padding-block:60px;
  }
  .section-head {
    margin-bottom:32px;
  }
  .head-row {
    grid-template-columns:1fr;
    gap:20px;
  }
  h2 {
    font-size:39px;
  }
  .project-facts {
    grid-template-columns:1fr;
    gap:0;
    margin-block:26px 36px;
    padding-block:20px;
  }
  .fact {
    padding-block:16px;
  }
  .fact+.fact {
    border-left:0;
    border-top:1px solid var(--line);
    padding-left:0;
  }
  .fact-number {
    font-size:56px;
  }
  .fact p {
    font-size:15px;
  }
  .steps-panel {
    padding:26px 20px 22px;
    border-radius:14px;
  }
  .steps-head {
    display:block;
    margin-bottom:24px;
  }
  .steps-head h3 {
    font-size:26px;
  }
  .steps-sub {
    display:none;
  }
  .research-steps {
    grid-template-columns:1fr;
    gap:14px;
  }
  .research-steps li {
    padding:22px 20px;
  }
  .step-no {
    margin-top:18px;
  }
  .steps-note {
    align-items:start;
    gap:12px;
    padding:17px 19px;
  }
  .challenge-box {
    flex-direction:column;
    align-items:flex-start;
    gap:18px;
    padding:26px 24px;
  }
  .challenge-marker {
    width:50px;
    height:50px;
    font-size:22px;
  }
  .preliminary {
    padding:26px 22px 24px;
    border-radius:14px;
  }
  .prelim-stats {
    grid-template-columns:1fr;
  }
  .prelim-stat strong {
    font-size:40px;
  }
  .impact-grid {
    grid-template-columns:1fr;
  }
  .js nav .nav-cta {
    flex:1 1 auto;
  }
  .pi-card {
    grid-template-columns:96px 1fr;
    gap:20px 16px;
    padding:24px 22px;
  }
  .pi-photo {
    width:88px;
    height:88px;
  }
  .pi-role {
    font-size:11px;
    margin-bottom:7px;
  }
  .pi-card h3 {
    font-size:25px;
  }
  .pi-expertise {
    grid-column:1 / -1;
    border-left:0;
    border-top:1px solid var(--line);
    padding:18px 0 0;
  }
  .team-groups {
    grid-template-columns:1fr;
    gap:26px;
  }
  .team-group {
    grid-template-columns:1fr;
    gap:14px;
  }
  .person {
    padding:26px 22px;
    text-align:center;
  }
  .person-photo {
    width:60px;
    height:60px;
    display:block;
    margin:0 auto 18px;
  }
  .person .profile-link {
    justify-content:center;
  }
  .person h4 {
    font-size:22px;
  }
  .team-growth {
    align-items:start;
    padding:17px 19px;
    font-size:14px;
  }
  .outcomes-status {
    flex-wrap:wrap;
    gap:14px;
    padding:19px 20px;
    margin-bottom:34px;
  }
  .outcomes-status>div {
    flex:1;
    min-width:165px;
  }
  .status-label {
    margin-left:42px;
    font-size:11px;
  }
  .publication-heading h3 {
    font-size:22px;
  }
  .publication {
    grid-template-columns:1fr;
    gap:20px;
    padding-block:24px;
  }
  .publication-visual {
    max-height:180px;
    overflow:hidden;
    border-radius:12px;
  }
  .publication-visual img {
    width:100%;
    height:180px;
    object-fit:cover;
    border:0;
  }
  .publication h4 {
    font-size:22px;
  }
  .text-link {
    min-height:40px;
  }
  .news-layout {
    grid-template-columns:1fr;
    gap:26px;
  }
  .news-layout h2 {
    font-size:39px;
  }
  .news-empty {
    flex-direction:row;
    gap:16px;
    padding:22px;
    border-radius:14px;
  }
  .news-illustration {
    width:95px;
  }
  .news-empty h3 {
    font-size:23px;
  }
  .contact-grid {
    grid-template-columns:1fr;
    gap:18px;
  }
  .contact-card {
    padding:25px;
  }
  .contact-logo,.contact-logo-unina {
    height:34px;
  }
  .contact-card h3 {
    font-size:27px;
  }
  .footer-grid {
    grid-template-columns:1fr;
    gap:30px;
    padding-bottom:32px;
  }
  .footer-brand {
    width:150px;
  }
  .footer-funding {
    grid-column:auto;
  }
  .footer-bottom {
    flex-direction:column;
    align-items:start;
    gap:8px;
    padding-block:16px;
  }
}

@media(prefers-reduced-motion:reduce) {
  html {
    scroll-behavior:auto;
  }
  *,*::before,*::after {
    transition:none!important;
    animation:none!important;
  }
  .button:hover,.button-ghost:hover,.contact-card:hover,
  .person:hover,.pi-card:hover {
    transform:none;
    box-shadow:none;
  }
}

@media print {
  .site-header,.hero-visual,.hero-actions,.skip-link {
    display:none;
  }
  .container {
    width:100%;
  }
  .section {
    padding-block:24px;
  }
  .hero {
    padding-block:0;
  }
  .hero-grid {
    display:block;
  }
  h1 {
    font-size:24px;
  }
  h2 {
    font-size:22px;
  }
  .pi-card,.steps-note,.team-growth,.outcomes-status,.preliminary,.challenge-box {
    print-color-adjust:exact;
    -webkit-print-color-adjust:exact;
  }
  .publication,.person,.contact-card,.research-steps li,
  .pillar,.disease-card,.impact-card,.prelim-stat {
    break-inside:avoid;
  }
  .js .reveal {
    opacity:1!important;
    transform:none!important;
  }
  .institutional-logos {
    width:245px;
    padding:35px;
  }
  .publication-visual {
    max-width:180px;
  }
  a {
    text-decoration:underline;
  }
  .footer-grid {
    grid-template-columns:1fr;
  }
}